| Date |
Opponent* |
Result |
Record |
|
| Sept. 4, 2010 | Wofford | W | 33-10 | 1-0 | | | Sept. 11, 2010 | Toledo | L | 20-13 | 1-1 (0-1) | | | Sept. 18, 2010 | at Ohio State | L | 43-7 | 1-2 | | | Sept. 25, 2010 | at Marshall | L | 24-23 | 1-3 | | | Oct. 2, 2010 | at Eastern Michigan | W | 30-17 | 2-3 (1-1) | | | Oct. 9, 2010 | Bowling Green | W | 49-25 | 3-3 (2-1) | | | Oct. 16, 2010 | Akron | W | 38-10 | 4-3 (3-1) | | | Oct. 23, 2010 | at Miami-OH | W | 34-13 | 5-3 (4-1) | | | Oct. 30, 2010 | Louisiana-Laf. | W | 38-31 | 6-3 | | | Nov. 4, 2010 | Buffalo | W | 34-17 | 7-3 (5-1) | | | Nov. 16, 2010 | at Temple | W | 31-23 | 8-3 | | | Nov. 26, 2010 | at Kent State | L | 28-6 | 8-4 (5-2) | | | Dec. 18, 2010 | at Troy | L | 48-21 | 8-5 | | |
| | | | |
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